Several years after winning Megalonia, Joe has become a shell of his former self. Now wandering underground rings as 'Nomad,' he fights while battling painkiller addiction and haunted by deceased coach Nanbu's memory. When Joe encounters struggling immigrants including former boxer Chief, he begins a journey of redemption. Confronting his past mistakes while attempting to rebuild what was lost, Joe faces new challenges that test not only his physical limits but his will to reclaim his humanity and find meaning in a life he thought was beyond saving.